Abstract Purpose: To evaluate the effect of aqueous extract of Baccharis trimera leaves on the proliferative capacity of the liver after partial hepatectomy (PH) in rats. Methods: Twenty Wistar rats weighing between 300 and 450g were divided into two groups: control (HP) and test (HP100-rats that received the aqueous extract of Baccharis trimera for four days at a dose of 100 mg / kg / day). On the fifth day, animals from both groups underwent resection of 70% of the liver. Twenty-four hours later, they were sacrificed and the remnant liver was removed and prepared for studied through PCNA immunohistochemistry. Data analysis for comparison between the two groups was made through the non-parametric statistical test Mann-Whitney test. Results: In all the animals studied was found most abundant nuclear immunostaining positive hepatocytes interlobular located in regions of the liver. Quantitative analysis of PCNA-positive cells revealed positivity rate significantly higher mean (p = 0.02) in HP100 group (77.1 ± 13.6) compared to the HP group (45.8 ± 12.9). Conclusion: DAdministration of aqueous extract of the leaves of Baccharis trimera 100 mg/kg of animal has a significant positive effect on liver regeneration in rats, 24 hours after hepatectomy (70%).

ABSTRACT PURPOSE: To assess the effect of aqueous extract of Peumus Boldus (AEPB) on the liver proliferative response after parcial hepatectomy of 70% (PH) in rodents. METHODS: Twenty Wistar rats were divided in two groups: AEPB100 (whose rats received 100mg/Kg of AEPB, once a day, orally, in 4 days prior to the first surgical procedure) and Vehicle (whose rats were treated similarly with distilled water). Both groups underwent PH. After 24 hours the remaining livers were removed for studying the proliferation of hepatocytes by Ki-67 and 2mL of blood were collected for serological assessment: cholesterol, glucose, triglycerides, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and total, direct and indirect bilirubin. All data were analyzed by Gaussian distribution. Statistically significant differences between mean values were analyzed using T Student's test. Non-Gaussian data were analyzed using Mann-Whitney's test. RESULTS: The liver of all these rats presented positive staining of Ki-67, indicating liver proliferation. Laboratory results showed no significant difference in serum values between the analyzed groups. The analysis of Ki-67 was significantly more positive in AEPB100 group than in Vehicle group. CONCLUSION: Aqueous extract of Peumus Boldus acute administration exerts significant positive effect on liver regeneration after 24h in rats that underwent parcial hepatectomy, while maintaining unchanged hepatic function.

Introdução:A própolis é uma substância resinosa e complexa; produzida pelas abelhas, destaca-se por suas propriedades terapêuticas, como atividade antimicrobiana, anti-inflamatória e cicatrizante. Poucos trabalhos existem sobre a variedade de própolis vermelha, encontrada no Estado de Sergipe.Objetivo:Avaliar a ação antimicrobiana do extrato de própolis vermelha, coletada na região nordeste do Estado de Sergipe, contra cepas de Enterococcus faecalis.Material e método:As amostras de própolis vermelha foram coletadas em Brejo Grande-SE, Brasil, e identificadas segundo suas características sensoriais, a granulometria e requisitos físico-químicos. O teor de flavonoides no extrato seco foi determinado. Soluções de própolis vermelha (EEP) foram preparadas nas concentrações de 1%; 2,5%; 5% e 7,5%. A cepa bacteriana de referência utilizada foi Enterococcus faecalis – ATCC 29212. A atividade antibacteriana foi verificada por meio de testes in vitro (teste de difusão em disco e determinação da concentração bactericida mínima – CBM) e ex vivo(utilizando dentes humanos extraídos). No teste ex vivo, os dentes contaminados foram divididos em três grupos com dez dentes cada. O grupo 1 foi tratado com própolis a 7,5% (concentração determinada no teste CBM); o grupo 2 foi tratado como controle positivo, com solução de hipoclorito de sódio a 2,5%, e o grupo 3 foi utilizado como controle negativo, sendo tratado apenas com solução salina NaCl 0,9%.Resultado:O extrato de própolis promoveu halo de inibição comparado ao da solução de hipoclorito de sódio a 2,5%, variando entre 12 e 16 mm. Não houve crescimento bacteriano após irrigação do conduto radicular com a solução de EEP a 7,5%.Conclusão:A própolis coletada apresentou médio teor de flavonoides (1,8%) e características físico-químicas coerentes com as exigidas pelo Ministério da Agricultura. Na concentração de 7,5% de própolis vermelha, foi observado um maior potencial antibacteriano quando comparado aos demais grupos.

Introduction:Propolis is a complex resinous substance produced by bees that has therapeutic properties, such as antimicrobial activity, anti-inflammatory, healing. Few studies exist on the red variety of propolis, found in the state of Sergipe.Objective:Evaluation of the antimicrobial action of the extract of propolis red collected in the northeastern state of Sergipe, against strains of Enterococcus faecalis.Material and method:The red propolis samples were collected in Brejo Grande/SE – Brazil and identified according to their sensory characteristics, granulometry and physical chemical requirements. The content of flavonoids in dried extract was determined. Solutions of red propolis (EEP) were prepared at concentrations of 1%; 2.5%; 5% and 7.5%. The bacterial strain used was Enterococcus faecalis – ATCC 29212. The antibacterial activity was verified by in vitro tests (disk diffusion test and determination of minimum bactericidal concentration – CBM) and ex vivo (using human extracted teeth). The test, ex vivo contaminated teeth were divided into three groups with 10 teeth each. Group 1 was treated with propolis to 7.5% (concentration determined in CBM test), the Group 2 was treated as positive control with sodium hypochlorite solution 2.5% and Group 3 was used as a negative control and was treated only with sterile saline.Result:The extract of propolis promoted inhibition zone compared to results from solution of sodium hypochlorite to 2.5%, showing values between 12 and 16 mm. There was no bacterial growth after root conduct irrigation with EEP to 7.5%.Conclusion:Propolis collected showed medium content of flavonoids (1.8%) and physical chemical characteristics consistent to those required by the Brazilian Government. At 7.5% of propolis extract, we observed a higher antibacterial potential than others groups.

The achievement of adequate levels of satisfaction at work ensures professionals' involvement and commitment to carry out their activities. On the other hand, low level of satisfaction may lead to loss in all dimensions of their existences, affecting their health, work, family and social relationships. Thus, the objective of this study was to evaluate the degree of satisfaction with working conditions on the part of professionals such as dental surgeons, physicians and nurses of the Family Health Strategy in the City of Aracaju, State of Sergipe, Brazil. To that end, we conducted a cross-sectional study with a descriptive approach. Data were collected using a structured questionnaire, previously validated, considering different issues relevant to the measurement of satisfaction with working conditions. The results showed low levels of satisfaction in the majority of the issues evaluated. Those referred to wages, health conditions and safety at work showed the lowest averages. The factor of greatest dissatisfaction for the professional categories studied was employment payments. We suggest that careful analyses of the working conditions of those professionals be carried out in addition to implementing actions in order to contribute to ensuring workers' satisfaction at work.

Conseguir niveles adecuados de satisfacción en el trabajo garantiza la participación y el compromiso de los profesionales en la realización de sus actividades. Por otra parte, el bajo nivel de satisfacción puede ocasionar daños en todas las dimensiones de sus existencias, afectando a la salud, al trabajo, a la familia y a sus relaciones sociales. Así, el objetivo de este estudio fue evaluar el grado de satisfacción con las condiciones de trabajo de profesionales como cirujanos dentistas, médicos y enfermeros de la Estrategia de Salud de la Familia de la Ciudad de Aracaju, Estado de Sergipe, Brasil. Con este fin, se realizó un estudio seccional de carácter descriptivo. Los datos fueron recolectados a través de un cuestionario estructurado, previamente validado, teniendo en cuenta diferentes dimensiones relevantes para la medición de la satisfacción con las condiciones de trabajo. Los resultados mostraron bajos niveles de satisfacción en la mayoría de las dimensiones evaluadas. Aquellas que se referían al salario, a las condiciones de la salud y a la seguridad en el trabajo tuvieron los promedios más bajos. El factor de mayor insatisfacción para las categorías profesionales evaluadas fue la remuneración salarial. Se sugiere realizar cuidadosos análisis de las condiciones de trabajo de esos profesionales y la ejecución de acciones con el propósito de contribuir a que haya satisfacción en el trabajo.

A obtenção de níveis adequados de satisfação no âmbito do trabalho garante envolvimento e comprometimento dos profissionais na execução de suas atividades. Por outro lado, baixo nível de satisfação pode acarretar prejuízo em todas as dimensões de suas existências, afetando a saúde, o trabalho, a família e as suas relações sociais. Desta forma, o objetivo deste trabalho foi avaliar o grau de satisfação com as condições de trabalho de profissionais como cirurgiões-dentistas, médicos e enfermeiros da Estratégia de Saúde da Família do Município de Aracaju, Estado de Sergipe, Brasil. Para tanto, foi efetuado um estudo seccional de cunho descritivo. Os dados foram coletados através de um questionário estruturado, previamente validado, considerando diferentes dimensões relevantes para aferição da satisfação com as condições do trabalho. Os resultados demonstraram baixos níveis de satisfação na maioria das dimensões avaliadas. Aquelas que se referiam ao salário, condições de saúde e segurança no trabalho apresentaram as menores médias. O fator de maior insatisfação para as categorias profissionais estudadas foi a remuneração salarial. Sugere-se a realização de uma análise criteriosa sobre as condições de trabalho desses profissionais e a efetivação de ações no intuito de contribuir para que haja satisfação no ambiente laboral.